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人工智能设计的通用新冠病毒疫苗通过首次人体试验

科学家研发了一种名为pEVAC-PS的广谱新冠疫苗,旨在同时预防SARS和新冠病毒。尽管疫苗在安全性上表现良好,但由于参与者抗体水平普遍较高,免疫增强效果不明显。这项研究验证了无针DNA疫苗的可行性,为应对沙贝科病毒大流行提供了基础数据。

人工智能设计的通用新冠病毒疫苗通过首次人体试验

极道
极道 · 2026-06-07T05:03:00Z

本文介绍了基于VHHs结构建立的大规模数据集AVIDa-hIL6,包含573,891个抗原-VHHs序列对,用于预测抗体-抗原相互作用。研究者提出了基于预训练模型的抗体设计方法,开发了AntiBERTy语言模型,并提出了IgBert和IgT5模型,推动抗体工程的发展。此外,研究还探讨了Vaxformer模型在疫苗设计中的应用及抗病毒药物资源库的建立。

一个 SARS-CoV-2 相互作用数据集和 VHH 序列语料库用于抗体语言模型

BriefGPT - AI 论文速递
BriefGPT - AI 论文速递 · 2024-05-29T00:00:00Z
SARS is Back in China

According to news report, more and more new SARS cases are discovered these days. 4 patients were discovered around the previous SARS patient found in Beijing. Image credit:...

SARS is Back in China

王建硕的博客
王建硕的博客 · 2004-04-26T01:10:36Z

Is SARS Coming Back to Shanghai? My answer: I did’t get any information about the SARS in Shanghai. I even didn’t hear about any rumor. I would say Shanghai is safe based on all the information I...

Is SARS Coming Back to

王建硕的博客
王建硕的博客 · 2004-01-23T14:33:38Z

With the new case of SARS in Taiwan, the alert level of Pudong Airport rised a little bit. I happen to go to the airport to pickup Wendy today. Passengers are asked to fillin the yellow health...

SARS Alert in Pudong Airport

王建硕的博客
王建硕的博客 · 2003-12-18T14:43:16Z

I was frightened that there become rumors that SARS cases emerge again in west part of China. Is it true? I hope not. Shanghai is still hot, exteremely hot. I started to be completely wet even...

SARS, Autumn Tiger, and MSF...

王建硕的博客
王建硕的博客 · 2003-08-26T15:10:03Z

I didn’t update SARS situation in Shanghai in the last week. So my readers like Tracey began to worry about the SARS sitautation. :-) Well. Let me tell you the current Shanghai in my eyes - it...

SARS Update in Shanghai

王建硕的博客
王建硕的博客 · 2003-06-16T15:24:56Z

SARS is over. After claiming the end of SARS two days ago, I feel even sure when all the information I gathered in the city these two days. Taxi drivers removed their masks According to Shanghai...

SARS is Over in Shanghai - II

王建硕的博客
王建硕的博客 · 2003-06-03T12:14:43Z
SARS is Over in Shanghai

This page contains personal opinions only. Don’t treat it as official announcement. If anyone asks me about the situation in Shanghai, I would say: “SARS is over in Shanghai”. Shanghai returns to...

SARS is Over in Shanghai

王建硕的博客
王建硕的博客 · 2003-06-01T14:20:30Z
Daily Life - SARS Related IV

This is the forth article of a series of article on the daily life in Shanghai. From the changes in MY life, you may get some idea about the real situation in Shanghai. Taxi If you read about my...

Daily Life - SARS Related IV

王建硕的博客
王建硕的博客 · 2003-05-26T14:28:25Z

As you can see from my recent weblog entries, I cover less SARS recent than in the month of April. This is also a reflection about how people in this city thinks about SARS - when the temperature...

SARS Almost Goes to an End

王建硕的博客
王建硕的博客 · 2003-05-19T13:18:10Z

The alarm level of Shanghai is raising to the newest level. Taxi From yesterday (May 11, 2003), all taxi drivers are required to wear masks. I noticed this at the morning. The taxi driver told us...

Shanghai SARS: The Next Level of Precaution

王建硕的博客
王建硕的博客 · 2003-05-12T11:44:16Z

6 SARS cases in Shanghai now. It is an alert. Althought there is only 4 new cases, it is 200% increase in the last few days by simply mathatics calculation. With the new cases, the alarm level of...

6 SARS Cases in Shanghai

王建硕的博客
王建硕的博客 · 2003-05-07T14:13:12Z

According to Shanghai Morning Post, two more SARS cases have been confirmed. They are a couple traveling to Shanghai. 42 intimate contacter and 63 indirect contacter have been tracked and related...

Two More SARS Cases in Shanghai

王建硕的博客
王建硕的博客 · 2003-05-04T14:20:33Z

This moring, when I chat with my friend Willie Liu of CultureXChina.com on MSN Messenger, he quoted: With SARS, All We Have is Time He is absolutely right. Long holiday, no outting May holiday...

With SARS, All We Have is Time

王建硕的博客
王建硕的博客 · 2003-05-02T01:30:42Z

It is the worst of time. April is the hard time for people in China - among the worst in my life (26 years). The impact to everyone’s life is comparable with the year of 1989 and the flood in...

SARS Shanghai - April Review

王建硕的博客
王建硕的博客 · 2003-04-30T14:54:17Z

Chat with taxi driver for the third time Taxi drivers are among the most sensitive people for any changes in the city. I initialized achat with the third taxi driver after SARS hit the city. If...

Daily Life - SARS Related III

王建硕的博客
王建硕的博客 · 2003-04-29T15:46:47Z

I went to a Taiwanese restaurant for dinner at about 8:00 PM. It seems the regulation of “wearing masks for all dining industry staff” is well executed. All the staff are wearing masks - the small...

My Dinner Impacted by SARS

王建硕的博客
王建硕的博客 · 2003-04-28T15:58:00Z

This is the second flash of dialy life from Shanghai in the SARS times. This is a sunny, warm Saturday in early spring. I stayed at home the whole day today. Fast Food Restraunts KFC in Metro City...

Daily Life - SARS Related II

王建硕的博客
王建硕的博客 · 2003-04-26T07:38:24Z
Protect China - Not Only Against SARS

To Google visitors Arrived here by searching China in Google Image? Welcome! I am Jian Shuo Wang, and I am living in Shanghai, China. I write one article everyday on this blog everyday since 2002....

Protect China - Not Only Against SARS

王建硕的博客
王建硕的博客 · 2003-04-25T15:02:37Z
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